High Levels of Interferon Gamma in the Plasma of Children With Complete Interferon Gamma Receptor Deficiency
نویسندگان
چکیده
منابع مشابه
High levels of interferon gamma in the plasma of children with complete interferon gamma receptor deficiency.
We have found that children with complete interferon gamma (IFNgamma) receptor deficiency, unlike patients with other genetic defects predisposing them to mycobacterial diseases, have very high levels of IFNgamma in their plasma. This unexpected observation provides a simple and accurate diagnostic method for complete IFNgamma receptor deficiency in children with clinical disease caused by baci...
متن کاملSerum Levels of Interferon-Gamma in Patients with Diabetic Retinopathy
Background: In recent years, numerous studies have addressed the role of other factors, especially the immune system, on developing diabetic retinopathy. Given the role of interferons in regulating immune system activities, the present study was conducted to investigate serum levels of interferon-gamma in patients with diabetic retinopathy. Materials and Methods: The present research was condu...
متن کاملThe Relationship of Serum Levels of Gamma Interferon and its Receptor (CD119) to Development of BCG Axillary Lymphadenopathy
Background: Lymphadenitis is the most common complication of BCG vaccination in children. Interferon-gamma (IFN-γ) plays a key role in immune response to Mycobacterial infections. In this study, the relationship of serum levels of IFN-γ and its receptor (CD119) to development of Bacillus Calmette Guerin (BCG) axillary lymphadenopathy was investigated. <em...
متن کاملLevel of Interferon Gamma in the Blood of Tuberculosis Patients
Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M. tuberculosis. It activates the production of other cytokines and molecules that kill mycobacterium. IFN-γ also has diagnostic role in identification of active and latent tuberculosis. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: Ninety...
متن کاملInducible Expression of Human Gamma Interferon
Background:The premature termination of high producer clones, which will be killed due to cell proliferation and proteins production antagonism, is one of the basic drawback in recombinant proteins technology. Furtheremore, it is supposed some toxic proteins like interferon which we intended to clone and express, inhibit host cells’ proliferation. So, it is necessary to tightly control IFN-γ pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatrics
سال: 2001
ISSN: 0031-4005,1098-4275
DOI: 10.1542/peds.107.4.e48